nav emailalert searchbtn searchbox tablepage yinyongbenwen piczone journalimg journalInfo journalinfonormal searchdiv searchzone qikanlogo popupnotification paper paperNew
2020, 02, v.8 87-93
影响注意缺陷多动障碍的营养因素及管理
基金项目(Foundation): 重庆市科卫联合医学科研重点项目(2018ZDXM012); 重庆市教育委员会研究生科研创新项目(CYS1919)
邮箱(Email):
DOI:
摘要:

注意缺陷多动障碍(attention-deficit/hyperactivity disorder,ADHD)是一种常见慢性神经发育障碍,起病于童年期,影响可延续至成年,其主要特征是与发育水平不符的注意缺陷和(或)多动冲动。在ADHD儿童的早期识别、诊断和规范治疗中,需重视营养因素对发病风险的影响、消化道症状和共患病对营养状况的影响,以及治疗和随访过程中对体格生长及营养水平的监测、评估和指导。实施ADHD儿童的营养管理将有助于减少ADHD儿童相关营养风险、改善营养状况,进一步提高治疗效果。

Abstract:

Attention-deficit/hyperactivity disorder( ADHD) is a common chronic neurodevelopmental disorder,which starts in childhood and can last to adulthood. The main characteristics of ADHD are attention deficit and/or hyperactivity impulse which are not commensurate with the development level. In the early identification,diagnosis and standardized treatment of ADHD children,attention should be paid to the influence of nutrition factors on the risk of disease,the influence of digestive tract symptoms and comorbidity on nutrition status,as well as the monitoring,evaluation and guidance of physical growth and nutrition level during treatment and follow-up. The nutritional management of ADHD children will help to reduce the related nutritional risks of ADHD children,improve the nutritional status,and increase curative effect.

参考文献

[1]中华医学会儿科学分会发育行为学组.注意缺陷多动障碍早期识别、规范诊断和治疗的儿科专家共识[J].中华儿科杂志,2020,58(3):188-193.

[2]Wolraich ML,Hagan JF Jr,Allan C,et al.Clinical practice guideline for the diagnosis,evaluation,and treatment of attention-deficit/hyperactivity disorder in children and adolescents[J].Pediatrics,2019,144(4):e20192528.

[3]Wang T,Liu K,Li Z,et al.Prevalence of attention deficit/hyperactivity disorder among children and adolescents in China:a systematic review and metaanalysis[J].BMC Psychiatry,2017,17(1):32.

[4]金星明,禹东川.注意缺陷多动障碍标准化门诊建设与规范化管理[M].北京:科学出版社,2019:1.

[5]陆林.沈渔邨精神病学[M].6版.北京:人民卫生出版社,2018.

[6]Biederman J,Faraone SV.Attention-deficit hyperactivity disorder[J].Lancet,2005,366(9481):237-248.

[7]Polańska K,Jurewicz J,Hanke W.Exposure to environmental and lifestyle factors and attention-deficit/hyperactivity disorder in childrend-a review of epidemiological studies[J].Int J Occup Med Environ Health,2012,25(4):330-355.

[8]Biederman J.Attention-deficit/hyperactivity disorder:a selective overview[J].Biol Psychiatry,2005,57(11):1215-1220.

[9]Biederman J,Faraone SV.Current concepts on the neurobiology of attention-deficit/hyperactivity disorder[J].J Atten Disord,2002,6(Suppl 1):S7-S16.

[10]Bekaroglu M,Asian Y,Gedik Y,et al.Relationships between serum free fatty acids and zinc,and attention deficit hyperactivity disorder:a research note[J].J Child Psychol Psychiatry,1996,37(2):225-227.

[11]Shareghfarid E,Sangsefidi ZS,Salehi-Abargouei A,et al.Empirically derived dietary patterns and food groups intake in relation with attention deficit/hyperactivity disorder(ADHD):a systematic review and meta-analysis[J].Clin Nutr ESPEN,2020(36):28-35.

[12]Hu FB.Dietary pattern analysis:a new direction in nutritional epidemiology[J].Curr Opin Lipidol,2002,13(1):3-9.

[13]Huijbregts P,Feskens E,Rsnen L,et al.Dietary pattern and 20 year mortality in elderly men in Finland,Italy,and the Netherlands:longitudinal cohort study[J].BMJ,1997,315(7099):13-17.

[14]Kant AK,Graubard BI,Schatzkin A.Dietary patterns predict mortality in a national cohort:the National Health Interview Surveys,1987 and 1992[J].J Nutr,2004,134(7):1793-1799.

[15]Wolosin SM,Richardson ME,Hennessey JG,et al.Abnormal cerebral cortex structure in children with ADHD[J].Hum Brain Mapp,2009,30(1):175-184.

[16]Norman LJ,Carlisi C,Lukito S,et al.Structural and functional brain abnormalities in attention-deficit/hyperactivity disorder and obsessive-compulsive disorder:a comparative meta-analysis[J].JAMA Psychiatry,2016,73(8):815-825.

[17]Huttenlocher PR,Dabholkar AS.Regional differences in synaptogenesis in human cerebral cortex[J].J Comp Neurol,1997,387(2):167-178.

[18]Barkley RA.Behavioral inhibition,sustained attention,and executive functions:constructing a unifying theory of ADHD.Psychol Bull,1997,121(1):65-94.

[19]Hung RJ,Yazdani U,Yoon J,et al.Mical links semaphorins to F-actin disassembly[J].Nature,2010,463(7282):823-827.

[20]Carey WB,Crocker AC,Elias ER,et al.Developmentalbehavioral pediatrics[M].4th ed.Philadelphia:Saunders Elsevier,2009.

[21]Azadbakht L,Esmaillzadeh A.Dietary patterns and attention deficit hyperactivity disorder among Iranian children[J].Nutrition,2012,28(3):242-249.

[22]Lee JK,Rhie SG.The effect of carbohydrate processed snacks on middle school students'emotional intelligence[J].Korean J Commun Living Sci,2008,19(3):335-351.

[23]Wiles NJ,Northstone K,Emmett P,et al.‘Junk food’diet and childhood behavioural problems:results from the ALSPAC cohort[J].Eur J Clin Nutr,2009,63(4):491-498.

[24]Del-Ponte B,Quinte GC,Cruz S,et al.Dietary patterns and attention deficit/hyperactivity disorder(ADHD):a systematic review and meta-analysis[J].J Affect Disord,2019(252):160-173.

[25]Simopoulos AP.Omega-3 fatty acids in health and disease and in growth and development[J].Am J Clin Nutr,1991,54(3):438-463.

[26]Freeman MP,Rapaport MH.Omega-3 fatty acids and depression:from cellular mechanisms to clinical care[J].J Clin Psychiatry,2011,72(2):258-259.

[27]Bloch MH,Mulqueen J.Nutritional supplements for the treatment of ADHD[J].Child Adolesc Psychiatr Clin NAm,2014,23(4):883-897.

[28]Bloch MH,Qawasmi A.Omega-3 fatty acid supplementation for the treatment of children with attention-deficit/hyperactivity disorder symptomatology:systematic review and meta-analysis[J].J Am Acad Child Adolesc Psychiatry,2011,50(10):991-1000.

[29]Hawkey E,Nigg JT.Omega-3 fatty acid and ADHD:blood level analysis and meta-analytic extension of supplementation trials[J].Clin Psychol Rev,2014,34(6):496-505.

[30]Musallam KM,Taher AT.Iron deficiency beyond erythropoiesis:should we be concerned?[J].Curr Med Res Opin,2018,34(1):81-93.

[31]Pivina L,Semenova Y,Do爧a MD,et al.Iron deficiency,cognitive functions,and neurobehavioral disorders in children[J].J Mol Neurosci,2019,68(1):1-10.

[32]Scassellati C,Bonvicini C,Faraone SV,et al.Biomarkers and attention-deficit/hyperactivity disorder:a systematic review and meta-analyses[J].J Am Acad Child Adolesc Psychiatry,2012,51(10):1003-1019.

[33]Palacios C,Gonzalez L.Is vitamin D deficiency a major global public health problem?[J].J Steroid Biochem Mol Biol,2014(144 Pt A):138-145.

[34]Berridge MJ.Vitamin D deficiency:infertility and neurodevelopmental diseases(attention-deficit/hyperactivity disorder,autism,and schizophrenia)[J].Am J Physiol Cell Physiol,2018,314(2):C135-C151.

[35]Patrick RP,Ames BN.Vitamin D hormone regulates serotonin synthesis.Part 1:relevance for autism[J].FASEB J,2014,28(6):2398-2413.

[36]Patrick RP,Ames BN.Vitamin D and the omega-3 fatty acids control serotonin synthesis and action.Part 2:relevance for ADHD,bipolar disorder,schizophrenia,and impulsive behavior[J].FASEB J,2015,29(6):2207-2222.

[37]Moretti R,Morelli ME,Caruso P.Vitamin D in neurological diseases:a rationale for a pathogenic impact[J].Int J Mol Sci,2018,19(8):2245.

[38]Pertile RA,Cui X,Eyles DW.Vitamin D signaling and the differentiation of developing dopamine systems[J].Neuroscience,2016(333):193-203.

[39]Pertile RA,Cui X,Hammond L,et al.Vitamin Dregulation of GDNF/Ret signaling in dopaminergic neurons[J].FASEB J,2018,32(2):819-828.

[40]Khoshbakht Y,Bidaki R,Salehi-Abargouei A.Vitamin Dstatus and attention-deficit hyperactivity disorder:a systematic review and meta-analysis of observational studies[J].Adv Nutr,2018,9(1):9-20.

[41]Mohammadpour N,Jazayeri S,Tehrani-Doost M,et al.Effect of vitamin D supplementation as adjunctive therapy to methylphenidate on ADHD symptoms:a randomized,double blind,placebo-controlled trial[J].Nutr Neurosci,2018,21(3):202-209.

[42]Dehbokri N,Noorazar G,Ghaffari A,et al.Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder[J].World J Pediatr,2019,15(1):78-84.

[43]Elshorbagy HH,Barseem NF,Abdelghani WE,et al.Impact of vitamin D supplementation on attention-deficit/hyperactivity disorder in children[J].Ann Pharmacother,2018,52(7):623-631.

[44]赵秋霞,陈立.儿童注意缺陷多动障碍药物依从性及影响因素[J].中国儿童保健杂志,2018,26(10):1096-1099.

[45]Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium.Psychiatric genome-wide association study analyses implicate neuronal,immune and histone pathways[J].Nat Neurosci,2015,18(2):199-209.

[46]Okun E,Griffioen K,Barak B,et al.Toll-like receptor 3inhibits memory retention and constrains adult hippocampal neurogenesis[J].Proc Natl Acad Sci USA,2010,107(35):15625-15630.

[47]Demontis D,Walters RK,Martin J,et al.Discovery of the first genome-wide significant risk loci for attentiondeficit/hyperactivity disorder[J].Nat Genet,2019,51(1):63-75.

[48]Kiwamoto T,Brummet ME,Wu F,et al.Mice deficient in the St3gal3 gene product alpha2,3 sialyltransferase(ST3Gal-Ⅲ)exhibit enhanced allergic eosinophilic airway inflammation[J].J Allergy Clin Immunol,2014,133(1):240-247.

[49]Yoo SW,Motari MG,Susuki K,et al.Sialylation regulates brain structure and function[J].FASEB J,2015,29(7):3040-3053.

[50]Hegvik TA,Instanes JT,Haavik J,et al.Associations between attention-deficit/hyperactivity disorder and autoimmune diseases are modified by sex:a populationbased cross-sectional study[J].Eur Child Adolesc Psychiatry,2018,27(5):663-675.

[51]郑毅,刘靖.中国注意缺陷多动障碍防治指南[M].2版.北京:中华医学电子音像出版社,2015.

[52]Clavenna A,Bonati M.Pediatric pharmacoepidemiologysafety and effectiveness of medicines for ADHD[J].Expert Opin Drug Saf,2017,16(12):1335-1345.

[53]Poulton AS,Bui Q,Melzer E,et al.Stimulant medication effects on growth and bone age in children with attentiondeficit/hyperactivity disorder:a prospective cohort study[J].Int Clin Psychopharmacol,2016,31(2):93-99.

[54]Schwartz BS,Bailey-Davis L,Bandeen-Roche K,et al.Attention deficit disorder,stimulant use,and childhood body mass index trajectory[J].Pediatrics,2014,133(4):668-676.

[55]NICE guideline.Attention-deficit hyperactivity disorder:diagnosis and management(NG87)[S].2018.

[56]ADHDexperts at ADDITUDE.5 rules for an ADHD-friendly diet[R].https://www.additudemag.com/download/adhd-friendly-diet-cooking-tips.

[57]Holton KF,Johnstone JM,Brandley ET,et al.Evaluation of dietary intake in children and college students with and without attention-deficit/hyperactivity disorder[J].Nutr Neurosci,2019,22(9):664-677.

[58]中国营养学会.中国居民膳食营养素参考摄入量(2013版)[M].北京:科学出版社,2014:6.

[59]Buttriss J.n-3 fatty acids and health.Nutr Bull,1999,24(2):71-73.

[60]Abd El-Hamid ZB,Refaat MM,El-Shahawy HH,et al.Impact of allergy on children with attention-deficit hyperactivity disorder[J].Eur Ann Allergy Clin Immunol,2018,50(6):262-267.

基本信息:

中图分类号:R749.94

引用信息:

[1]陈立.影响注意缺陷多动障碍的营养因素及管理[J].教育生物学杂志,2020,8(02):87-93.

基金信息:

重庆市科卫联合医学科研重点项目(2018ZDXM012); 重庆市教育委员会研究生科研创新项目(CYS1919)

发布时间:

2020-06-15

出版时间:

2020-06-15

引用

GB/T 7714-2015 格式引文
MLA格式引文
APA格式引文